Bronchiolitis Obliterans with Organizing Pneumonia (BOOP)

Bronchiolitis obliterans with organizing pneumonia Definition

Bronchiolitis obliterans organizing pneumonia (BOOP) is a pathologic finding common to various injuries to the lung of either definite or idiopathic etiology. Bronchiolitis obliterans organizing pneumonia is a distinct entity among the spectrum of infiltrative lung diseases without apparent causes or associated diseases. BOOP may be characterized by polyploid endobronchial connective tissue.

Men and women equally affected by BOOP and usually aged in between 50 to 60. Bronchiolitis obliterans with organizing pneumonia (BOOP), also known as cryptogenic organizing pneumonia.

Bronchiolitis obliterans with organizing pneumonia causes

In many cases, the cause of Bronchiolitis obliterans organizing pneumonia can't be determined. Bronchiolitis obliterans and organizing pneumonia may be associated with specific diseases or situations, such as bone marrow, heart, or heart-lung tranplantation. Bronchiolitis obliterans organizing pneumonia means inflammation of the bronchioles. Bronchiolitis obliterans organizing pneumonia may be developed in the allograft lung.

The main causes of Bronchiolitis obliterans with organizing pneumonia may be included:

• Certain medications
• Radiation therapy for breast cancer
• Bone marrow transplants
• Organ and tissue transplantation
• Certain connective tissue disorders, such as lupus

Bronchiolitis obliterans with organizing pneumonia symptoms

In some people, bronchiolitis obliterans with organizing pneumonia causes no signs or symptoms.

The main symptoms of Bronchiolitis obliterans with organizing pneumonia may be included:

• cough
• fever
• persistent
• dyspnea
• malaise
• anorexia
• chest pain
• night sweats
• diffuse Alveolar Damage
• influenza-like symptoms
• chronic Fibrous Pneumonia
• fibrous Interstitial Pneumonia

Bronchiolitis obliterans with organizing pneumonia treatments

Patients with asymptomatic mass lesions or nonprogressive disease may be observed and treated at a later time if needed.

Corticosteroids may be used in the treatment of bronchiolitis obliterans with organizing pneumonia.

In most cases, treatment begins with 1 mg/kg/day of prednisone for at least several days to several weeks.

The patient may be need either no oxygen or a small amount of oxygen at rest and a greater amount during exercise.